| Date | Opponent | Time | Score | Info | |
| Sep 4, 2010 | at Hardin-Simmons Short Course | Preview | |||
| Sea Bee Park | |||||
| Sep 11, 2010 | at New Mexico JC | ||||
| Hobbs, NM | |||||
| Sep 18, 2010 | at HSU High School Meet | Preview | |||
| Sea Bee Park -- HSU will host but not run | |||||
| Sep 25, 2010 | at Division III State Meet | ||||
| Seguin, Texas | |||||
| Oct 1, 2010 | at West Texas A&M | ||||
| Canyon, Texas | |||||
| Oct 16, 2010 | at UT-Permian Basin | ||||
| Odessa, Texas | |||||
| Oct 30, 2010 | at ASC Championship | ||||
| Tyler, Texas | |||||
| Nov 13, 2010 | at NCAA South/Southeast Regional | ||||
| Memphis, Tenn. | |||||
| Nov 20, 2010 | at NCAA Championship | ||||
| Waverly, Iowa | |||||
